[Music]
which here has the fear of aging and hand
you are many but in the
aging it ‘s not just fear
it’s not just the horror that here a
good memory of his grandfather or his
grandmother’s hand you’re still
more numerous in aging
there is this duality this ambiguity
we have a positive perception our
loving grandparents attentive their
memory their love and then this
negative perception
fear fear of decrepitude
fear of disease
the fear of death and made him
aging is accompanied by illness
there is a large community of
researchers of which I am a part
fight and fight diseases
related to aging and research
advance the research is rapidly advancing
in the early 90s we find
the first gene able to increase the
longevity of an animal a small glass
a hematoma a millimeter long
but still an animal in the
2000s we find a gene capable
to increase the longevity of a mouse
it’s a much closer mammal
of us in 2009 it’s more of a gene but
a molecule capable of increasing the
longevity of this same smile and
today we are looking for
drugs that might
possibly go into trial
clinic to treat diseases of the
aging in humans
so of course it’s progress
less suffering less diseases
it’s fewer cancers less diseases
degenerative less diseases
cardiovascular but in parallel with
this race there is a movement that
is called transhumanism maybe
have you ever heard of it?
the approach to death the man who will live
kite
this race there is not quite
of the same nature
of course it is based on momentum and
the speed with which
research is advancing but the rhetoric
transhumanists is pretty violent
it puts you under the accomplished fact
the man who will live milan is already born
and this conviction
this absolute perception is actually
based on an old fear is good
understandable
the fear of dying so where to put the
slider that believe and not believe
to answer this question you have to
go back a bit and land
basic questions is the first
questions is what is the
aging most of us
think of aging as the
wear process like a suge t-shirt
and tear apart our body ages and
dies
but biology shows us that in fact
it is not so simple
biology shows us that the process
aging is not mandatory
neither systematic
there are organisms like hydra
who do not age the hydra is a
little aquatic being that actually
seems not to age
so that may seem like an anecdote
but it teaches us something
importantly it teaches us that the
aging is not synonymous with
living in fact living it’s
precisely the ability to propagate
life from one generation to another
is to make sure that this son of the
city never stop each other
obviously the transhumanists get
take this observation and you
tell if the hydra can do it why
not us this observation tell you
as well as aging
it’s not exactly like measure
so why are we aging
may seem trivial
but she is not so much
since the aged hydra does not age
and us if
it is very difficult to answer with
certainty to this question but we can
start thinking about some
items
it exists with respect to the ability to
spread life several strategies and
when I talk about strategy I’m talking about
evolutionary choices that were made there
are millions of years through
aging
there is the hydra strategy of which
most cells are able to
to regenerate and rejuvenate himself and he
our strategy exists and we have
concentrated our ability to
regeneration and rejuvenation
in a very small number of cells
these cells these are the cells of the
reproduction
we call them germ cells
every time we breed ourselves
we rejuvenate every time
we make a baby our cells
Germ cells produce cells
rejuvenated who themselves will produce
a baby who will be born at age
0 it may sound obvious but it’s
not that simple how two be
mature alger are able to produce
a new being is exactly what
is different if the living of the inert
so
our immortality it actually resides
in our children so why have
chosen chose this strategy rather
than another
again it is very difficult
to respond firmly to a
question like this but what we
note is that very often the
aging organisms are often
more complex we made the choice
to focus our ancestral capacity
to transmit life in a very small
number of cells and suddenly we have
could develop many more
cells that are able to fill
many other functions
these cells are the cells
somatic all cells that is not
germinal is a somatic cell and
these cells are in charge of filling
all the functions that are not
those of reproduction and detail
and the specificity of the functions that
these cells are able to fill and
fascinating a muscle cell can get
to contract a nerve cell can
produce an electric current that
crosses our body and that synchronizes
its action thanks to cells
somatic we can see we
can we run we can dance we
can think we can love
so let’s think we like cells
somatic are extremely
diversified and we can see that he
exists an antagonism between the capacity
to perform these tasks very
specialized and the ability to
regenerate
these fascinating cells have developed
extraordinary abilities but
they lost their original capacity
of rejuvenation
as these cells constitute the
main part of our being and
as it ages we get older
also these cells gives color
to our life is actually these cells
who gives our grandparents those
characteristics that we love them
memory their love their look we see
so although the first intuition that
aging is not necessarily
something negative is true
there is positive in aging
and dia positive in its raison d’être
biological
while what to do
in front of the screw of course you have to
continue to search
we must continue to understand and I
join me in this research movement
which constitutes to understand the ways
metabolic processes that will allow us to
cure the diseases of aging
as we have cured the diseases
infectious and we will get there
the other proposal the proposal
transhumanists is a proposition
radically different
she offers you to move to
immortality is what this is
possible
difficult to answer will get us
to be immortal without losing our
somatic functions not so obvious that
that is what is desirable
even less obvious in any case
better understand now that
contrary to what rhetoric
transhumanists said he will not be so
simple to make immortal because he
will change our architecture
whole to come back on choices
evolutionary that have indeed been done there
millions of years ago while
to do before aging think
look for love thank you
[Applause]
which here has the fear of aging and hand
you are many but in the
aging it ‘s not just fear
it’s not just the horror that here a
good memory of his grandfather or his
grandmother’s hand you’re still
more numerous in aging
there is this duality this ambiguity
we have a positive perception our
loving grandparents attentive their
memory their love and then this
negative perception
fear fear of decrepitude
fear of disease
the fear of death and made him
aging is accompanied by illness
there is a large community of
researchers of which I am a part
fight and fight diseases
related to aging and research
advance the research is rapidly advancing
in the early 90s we find
the first gene able to increase the
longevity of an animal a small glass
a hematoma a millimeter long
but still an animal in the
2000s we find a gene capable
to increase the longevity of a mouse
it’s a much closer mammal
of us in 2009 it’s more of a gene but
a molecule capable of increasing the
longevity of this same smile and
today we are looking for
drugs that might
possibly go into trial
clinic to treat diseases of the
aging in humans
so of course it’s progress
less suffering less diseases
it’s fewer cancers less diseases
degenerative less diseases
cardiovascular but in parallel with
this race there is a movement that
is called transhumanism maybe
have you ever heard of it?
the approach to death the man who will live
kite
this race there is not quite
of the same nature
of course it is based on momentum and
the speed with which
research is advancing but the rhetoric
transhumanists is pretty violent
it puts you under the accomplished fact
the man who will live milan is already born
and this conviction
this absolute perception is actually
based on an old fear is good
understandable
the fear of dying so where to put the
slider that believe and not believe
to answer this question you have to
go back a bit and land
basic questions is the first
questions is what is the
aging most of us
think of aging as the
wear process like a suge t-shirt
and tear apart our body ages and
dies
but biology shows us that in fact
it is not so simple
biology shows us that the process
aging is not mandatory
neither systematic
there are organisms like hydra
who do not age the hydra is a
little aquatic being that actually
seems not to age
so that may seem like an anecdote
but it teaches us something
importantly it teaches us that the
aging is not synonymous with
living in fact living it’s
precisely the ability to propagate
life from one generation to another
is to make sure that this son of the
city never stop each other
obviously the transhumanists get
take this observation and you
tell if the hydra can do it why
not us this observation tell you
as well as aging
it’s not exactly like measure
so why are we aging
may seem trivial
but she is not so much
since the aged hydra does not age
and us if
it is very difficult to answer with
certainty to this question but we can
start thinking about some
items
it exists with respect to the ability to
spread life several strategies and
when I talk about strategy I’m talking about
evolutionary choices that were made there
are millions of years through
aging
there is the hydra strategy of which
most cells are able to
to regenerate and rejuvenate himself and he
our strategy exists and we have
concentrated our ability to
regeneration and rejuvenation
in a very small number of cells
these cells these are the cells of the
reproduction
we call them germ cells
every time we breed ourselves
we rejuvenate every time
we make a baby our cells
Germ cells produce cells
rejuvenated who themselves will produce
a baby who will be born at age
0 it may sound obvious but it’s
not that simple how two be
mature alger are able to produce
a new being is exactly what
is different if the living of the inert
so
our immortality it actually resides
in our children so why have
chosen chose this strategy rather
than another
again it is very difficult
to respond firmly to a
question like this but what we
note is that very often the
aging organisms are often
more complex we made the choice
to focus our ancestral capacity
to transmit life in a very small
number of cells and suddenly we have
could develop many more
cells that are able to fill
many other functions
these cells are the cells
somatic all cells that is not
germinal is a somatic cell and
these cells are in charge of filling
all the functions that are not
those of reproduction and detail
and the specificity of the functions that
these cells are able to fill and
fascinating a muscle cell can get
to contract a nerve cell can
produce an electric current that
crosses our body and that synchronizes
its action thanks to cells
somatic we can see we
can we run we can dance we
can think we can love
so let’s think we like cells
somatic are extremely
diversified and we can see that he
exists an antagonism between the capacity
to perform these tasks very
specialized and the ability to
regenerate
these fascinating cells have developed
extraordinary abilities but
they lost their original capacity
of rejuvenation
as these cells constitute the
main part of our being and
as it ages we get older
also these cells gives color
to our life is actually these cells
who gives our grandparents those
characteristics that we love them
memory their love their look we see
so although the first intuition that
aging is not necessarily
something negative is true
there is positive in aging
and dia positive in its raison d’être
biological
while what to do
in front of the screw of course you have to
continue to search
we must continue to understand and I
join me in this research movement
which constitutes to understand the ways
metabolic processes that will allow us to
cure the diseases of aging
as we have cured the diseases
infectious and we will get there
the other proposal the proposal
transhumanists is a proposition
radically different
she offers you to move to
immortality is what this is
possible
difficult to answer will get us
to be immortal without losing our
somatic functions not so obvious that
that is what is desirable
even less obvious in any case
better understand now that
contrary to what rhetoric
transhumanists said he will not be so
simple to make immortal because he
will change our architecture
whole to come back on choices
evolutionary that have indeed been done there
millions of years ago while
to do before aging think
look for love thank you
[Applause]
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