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IT IS ABOUT TIME TO INDIVIDUALIZE CANCER TREATMENT | Dr. Michele Carpenter | TEDxCanonDriveWomen


so in in preparation for being here

today one of our coaches who said to me

so why do you do what you do so the

reason I do what I do is that when I was

going through Medical School I realized

that I was a fixer and I needed to fix

things so he became a general surgeon

and as I went into general surgery more

and more of my patients would say you’re

not a typical surgeon and I’d say what

do you mean by that will you talk to my

to us you talk as if we’re really

important and you’re not here just to

operate and so that’s how I ended up in

breast cancer surgery because my day

starts usually with many worried women

and I’ll give you a little story about

how that goes I walk into an exam room

and there she is

sometimes with a significant other and

sometimes not and she’s sitting on the

table and she’s looking like a deer in

the headlights

and she most of the time at this point

knows that she has breast cancer and the

first thing I have to do is I have to

walk up to her and hold her hands and

say this is curable because breast

cancer is curable and the thing about

breast cancer is that breast cancer is

not just one disease it’s at least four

different diseases and in about the year

2000 and Scientific American there was a

scientific article that said it may not

just be for diseases it may be ten

different varieties of disease and so

what I try to tell them even though

they’re sitting there with a pile of

papers from dr. Google is that we have

to treat breast cancer individually we

have to understand what kind of breast

cancer this particular patient has so

I’m going to take you through a journey

a journey that will look at what breast

cancer has been and where we’ve come

when it comes to surgery

because over the course of time

especially since the late 1970s we’ve

added other treatment options to the

surgical treatment of breast cancer and

those are not what we’re going to talk

about today those include hormonal

treatment and chemotherapy putting me to

guess we don’t have another slide ok I

had a diagram next one these are the

faces of breast cancer these are the

patients who you all see on a daily

basis in your Ladies Home Journal and in

the People magazine these are young

these are old these are the celebrities

they come in African American and Asian

they’re men I swear this was amazed that

Richard Roundtree actually had breast

cancer in 1993 and Peter Criss of KISS

had breast cancer so this is what you

wouldn’t it be great if we actually were

able to take care of breast cancer in a

one-day kind of fashion where did we

come from though

next the picture on your left is a

picture of a very ancient instrument

that was how we used to remove not that

I ever did I wasn’t that old but remove

the breast the picture on your right is

the modern-day giant and surgery dr.

Halstead dr. Halsted did what we learn

to be one of the major reasons that we

could cure breast cancer is the radical

mastectomy the radical mastectomy

actually was everything that we could

find on the chest wall it cured more

patients but the problem is when you

cure more patients we also at that type

of surgery we did a lot more disfiguring

teachers so by the 1970s we realized we

didn’t have to do radical procedures so

in the late 1970s we just left the

muscle in place and we took the breast

we would give the patient a very nice

flat chest and these slides are not my

slides that my latest version so I’m

going to apologize because I had some

really good pictures for you so I know

they’re not going to be here and so it’s

making me Norbit more nervous so I’m

just going to tell you this story when

we do the modified radical mastectomy we

leave the muscle and we take less lymph

nodes

what happened was we realized that we

didn’t have to always take all those

lymph nodes and we could just take the

lower two levels we still did

mastectomies but what we found is that

we could actually reconstruct the breast

and we could reconstruct the breast and

make it look almost like you were born

with well over the last 10 years we

actually realized that we could take the

breast leave the nipple in place in the

correct patient and the patient would

look almost like themselves I wish I had

my slides because I could show you a

patient who gave me permission to show

you what she looks like and she has two

breasts one is fake and the other one is

hers and they look identical but by the

1980s we realized that what we could do

is we could take a portion of the breast

and by taking a portion of the breast

and a little rim of normal tissue we can

make that patient live just as long as

the mastectomy patient but we needed to

do radiation and in the 1980s when we

did this study what we realized was that

radiation had to be the whole breast ten

minutes a day five days a week for six

well that’s fast-forward now about 15 to

18 years ago what we also found is that

maybe we can do less maybe more is less

and so what we did was

we started to use partial breast

radiation techniques where we actually

insert a device into the breast after

the fact and the patient would go to the

radiation facility they’d have this

device sticking out of their breast now

mind you it was bandaged in between so

we didn’t have to make them walk around

with this device fluttering in the wind

and so what they would do is up to this

machine and just radiate the area around

the breast tumor cavity and when they

did that we were able to do it in a

shorter time period twice a day for five

days and the catheter only had to be in

there for a week it decreased the amount

of radiation damage to the rest of the

chest wall but not everybody could have

this but a good portion of our patients

could do this so about 10 plus years ago

some very bright people said why can’t

we do this in the operating room

wouldn’t this be wonderful to have it

done all at the same time so there are

three different types of equipment that

have been used to do this intraoperative

radiation two of them use a low-voltage

type of equipment and one uses electrons

all three are still being used today but

in September the American Society of

radiation oncologists actually published

some guidelines that now makes it that

it can be used outside of an

experimental study because up until this

last month everything that we did

interoperative ly really was under an

experimental study electrons electrons

is the type of radiation that we are

most comfortable with it’s what we’re

used to being able to manipulate to do

treatment for all types of cancer

including breast cancer and so what we

now have at our disposal is the ability

to tell a patient that we can do it all

at the same time not everybody can have

this it has to be a patient with a small

tumor someone who doesn’t have any

cancer in their lymph nodes at the

time and it has to be something that we

can actually do and feel comfortable

about doing so I had a patient she came

to me recently and she walked and I told

you about dr. Google well they also come

in not even knowing what kind of cancers

they have and she said to me before you

even start I will only have an incision

this big I am NOT doing chemo I won’t

take that hormone blocking pill and I

want it all done at one time okay so the

good news is she fit all the criteria

but there was one thing I had to tell

her the machine I do radiation with me

and her incision has to be bigger and

she said well how big and I said I can’t

tell you as big as I have to make it I

won’t guarantee a nice you have to

guarantee me I said I can’t guarantee I

said I can guarantee that you’ll be

happy I’ll do it all at one time

and I’ll try to hide most of your scar

so it took me a while she had to go away

and come back a couple of times just to

get to the point where she could be calm

about her decision but we did it and

even though her incision was not this

big when she came back a week after

surgery she said okay you were right

it’s okay so the take-home message today

really is that breast cancer is curable

and we can do more in a smaller amount

of time with less treatment if we find

it early

yes breast cancer is scary and yes

everybody should have knowledge and

education about what their diseases

before they come in for treatment and

can make that decision and for all the

women in the audience get your

mammograms thank you [Applause]

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