one in a million what are the odds
welcome to watchmojo.com and today we’re
counting down our picks for the top ten
rarest conditions and diseases fop is
one of the rarest conditions known to
mankind
before we begin we publish new videos
every day so be sure to subscribe for
more great content for this list we’re
ranking the medical conditions that
occur the least among the human
population these diseases either tend to
be found in one specific area of the
world or otherwise rarely present within
large groups of people and tend to carry
with them some very bizarre symptoms one
leg swollen more than double the size of
the other her skin hot and thick number
10 foreign accent syndrome between 1941
and 2009 62 cases of the speech
condition known as foreign accent
syndrome or FAS were reported first
discovered in 1907 FAS is characterized
by the subject speaking their native
language with an accent that is foreign
to them oh you’re visiting we’ll put a
rush on you for all ongoing why are
people saying this so imagine a born and
raised New Yorker suddenly speaking with
a deep Southern drawl or like a member
of the British aristocracy Simon I can
summation it what does a chances in some
cases rather than an accent
a person’s pitch or ability to correctly
pronounce syllables may be affected say
it again bagel
SAS can be brought on by a stroke or
some form of head trauma with patients
sometimes comparing the symptoms to
those associated with a speech disorder
she turned up after having a nasty head
injury eight years ago speaking with a
French accent
can’t believe my ears number nine
microcephaly the connection between the
Zika virus in pregnant women and
children’s born with microcephaly
brought significant attention to this
disorder microcephaly generally presents
at birth or early in a child’s
development children born with the
condition exhibit a lack of brain
development and a
head much smaller than normal side
effects include intellectual
disabilities and low motor function as
well as a propensity for seizures and
dwarfism the lifespan is also typically
affected although there have been cases
where those suffering from this
condition went on to lead a normal life
usually the impaired brain function has
a significant negative impact but it’s
not the end of solutions because you
have these kids they would teach them so
much number eight
epidermal dysplasia bruise the form of
the human body is a strange and
mysterious thing that can fall victim to
a number of equally strange diseases
case in point the hereditary skin
disease epidermidis plays abruzzo formas
also known as the tree man illness the
disease which is often abbreviated to
evey occurs as a result of a pH mutation
within the genes evey affects the body’s
resilience to human papillomaviruses on
the skin often infecting the patient
with uncontrolled scale-like growth
these growths often take on the
appearance of tree-like appendages
growing from the hands or feet
remarkably resistant to both medication
and surgery evey patients have been
treated with some success but they
usually require repeated treatment
number seven fibro dysplasia ossificans
progressiva
our bodies can be incredibly efficient
healing machines but what happens when
that natural repair process goes wrong
this is the situation with fibro
dysplasia ossificans progressiva
or FOP this disease of the connective
tissue affects the body’s ability to
naturally heal supply of fibrous tissue
like muscles joints and ligaments
translation when someone uplifted with
FOP is injured their body repairs itself
not by growing healthy new tissue but by
growing foam sometimes this results in
joints that are literally frozen by the
process of ossification and it causes my
muscles and connective tissues to turn
to bone number six hutchinson-gilford
progeria syndrome all those a Curious
Case of Benjamin Button is this who have
been inspired by hutchinson-gilford
progeria syndrome the condition in real
life is quite different however body
else was aging
was kidding element babies born with
this extremely rare genetic disorder
often simply called progeria aim to age
at a vastly accelerated rate few live
beyond their early 20s and most exhibit
symptoms of the disease shortly after
birth these symptoms start with a
failure to fly those other babies do
along with a hardening of the skin other
symptoms include brittle bones hair loss
reduced eyesight wrinkled skin and
excessive weight loss essentially the
young child seems to be aging way faster
than they should be and sadly there is
no cure number 5 Harlequin type Dixie
OSIS remarkable advances in the area of
neonatal care have proven to be a
godsend for those suffering from the
extremely rare skin condition known as
Harlequin type exposes this disease is
distinguished by the presence of a thick
hard armor-like plate of dry skin all
over the body dehydration and
respiratory issues are common as is
serious infection due to the skins
cracked arid nature this disease was
almost always fatal to infants when it
was first seen during the mid 1700s
today however early care and treatment
means that babies born with Harlequin
type XP osis now have a fighting chance
for survival when I get such ignorant
sand things it does chip away and I just
hope it doesn’t completely take take my
confidence away number four congenital
analgesia we’ve all day dreamed about
being a superhero and being able to
withstand an enormous amount of pain or
damage without batting an eye could you
do this harder what would happen if we
actually couldn’t feel any pain
whatsoever what this really be a good
thing not according to those who suffer
from congenital analgesia a rare and
dangerous disorder which does just that
it affects the body’s ability to feel
pain doctors believe an excessive amount
of endorphins produced in the brain
caused this condition unfortunately this
exacerbates damage to the body rather
than diminishing it many of those
afflicted by CA have reported biting off
their own tongue breaking bones or
suffering severe in
action number three ahlstrom syndrome
Ostrom syndrome or ahlstrom halgren
syndrome as it’s sometimes known is one
of the most recently discovered
conditions on our list first reported in
1959 by Swedish psychiatrist Carl Henry
Ostrom it’s also one of the rarest
conditions with just over 500 cases
having been reported all over the world
ahlstrom syndrome can usually be seen in
infancy characterized by a wide array of
severe organ issues obesity blindness
loss of hearing and diabetes are just a
few of the symptoms associated with AF
if you live past age 50 due largely to
the fact that there’s currently no cure
for the disease only therapy and
treatment number two fields disease no
medical condition is rarer than the
neuromuscular condition known as Fields
disease only two cases have been
reported to date the twin sisters
Catherine and Kirsty fields for whom the
disease is named in 1998 their parents
noticed some initial problems within
five years the girls were suffering from
severe muscular degeneration eventually
losing their ability to speak and
requiring Walker’s to assist in mobility
meanwhile neurological issues caused
severe shaking and trembling hands so
difficult to manage a 2012 update from
Britain’s Daily Mirror showed the girls
in good spirits after they were given
speech devices similar to those used by
Stephen Hawking before we named our
rarest medical conditions here are some
honorable mentions
[Music]
number one aquagenic urticaria some
people can’t swim some folks just hate
the water water never touch the stuff
fish in it but what if exposure to h2o
actually caused you intense physical
pain
those who suffer from aquagenic
urticaria an intense skin reaction to
water contend with this problem on a
daily basis red itchy hives can emerge
on the skin only minutes after exposure
what’s more there’s no cure for
aquagenic urticaria which is more likely
to occur in women than men only
antihistamine steroids radiation or
medication offer limited comfort to
those for whom every shower or hand
washing session is a challenge do you
agree with our pics check out these
other great clips from WatchMojo and
subscribe for new videos every day
[Music]
welcome to watchmojo.com and today we’re
counting down our picks for the top ten
rarest conditions and diseases fop is
one of the rarest conditions known to
mankind
before we begin we publish new videos
every day so be sure to subscribe for
more great content for this list we’re
ranking the medical conditions that
occur the least among the human
population these diseases either tend to
be found in one specific area of the
world or otherwise rarely present within
large groups of people and tend to carry
with them some very bizarre symptoms one
leg swollen more than double the size of
the other her skin hot and thick number
10 foreign accent syndrome between 1941
and 2009 62 cases of the speech
condition known as foreign accent
syndrome or FAS were reported first
discovered in 1907 FAS is characterized
by the subject speaking their native
language with an accent that is foreign
to them oh you’re visiting we’ll put a
rush on you for all ongoing why are
people saying this so imagine a born and
raised New Yorker suddenly speaking with
a deep Southern drawl or like a member
of the British aristocracy Simon I can
summation it what does a chances in some
cases rather than an accent
a person’s pitch or ability to correctly
pronounce syllables may be affected say
it again bagel
SAS can be brought on by a stroke or
some form of head trauma with patients
sometimes comparing the symptoms to
those associated with a speech disorder
she turned up after having a nasty head
injury eight years ago speaking with a
French accent
can’t believe my ears number nine
microcephaly the connection between the
Zika virus in pregnant women and
children’s born with microcephaly
brought significant attention to this
disorder microcephaly generally presents
at birth or early in a child’s
development children born with the
condition exhibit a lack of brain
development and a
head much smaller than normal side
effects include intellectual
disabilities and low motor function as
well as a propensity for seizures and
dwarfism the lifespan is also typically
affected although there have been cases
where those suffering from this
condition went on to lead a normal life
usually the impaired brain function has
a significant negative impact but it’s
not the end of solutions because you
have these kids they would teach them so
much number eight
epidermal dysplasia bruise the form of
the human body is a strange and
mysterious thing that can fall victim to
a number of equally strange diseases
case in point the hereditary skin
disease epidermidis plays abruzzo formas
also known as the tree man illness the
disease which is often abbreviated to
evey occurs as a result of a pH mutation
within the genes evey affects the body’s
resilience to human papillomaviruses on
the skin often infecting the patient
with uncontrolled scale-like growth
these growths often take on the
appearance of tree-like appendages
growing from the hands or feet
remarkably resistant to both medication
and surgery evey patients have been
treated with some success but they
usually require repeated treatment
number seven fibro dysplasia ossificans
progressiva
our bodies can be incredibly efficient
healing machines but what happens when
that natural repair process goes wrong
this is the situation with fibro
dysplasia ossificans progressiva
or FOP this disease of the connective
tissue affects the body’s ability to
naturally heal supply of fibrous tissue
like muscles joints and ligaments
translation when someone uplifted with
FOP is injured their body repairs itself
not by growing healthy new tissue but by
growing foam sometimes this results in
joints that are literally frozen by the
process of ossification and it causes my
muscles and connective tissues to turn
to bone number six hutchinson-gilford
progeria syndrome all those a Curious
Case of Benjamin Button is this who have
been inspired by hutchinson-gilford
progeria syndrome the condition in real
life is quite different however body
else was aging
was kidding element babies born with
this extremely rare genetic disorder
often simply called progeria aim to age
at a vastly accelerated rate few live
beyond their early 20s and most exhibit
symptoms of the disease shortly after
birth these symptoms start with a
failure to fly those other babies do
along with a hardening of the skin other
symptoms include brittle bones hair loss
reduced eyesight wrinkled skin and
excessive weight loss essentially the
young child seems to be aging way faster
than they should be and sadly there is
no cure number 5 Harlequin type Dixie
OSIS remarkable advances in the area of
neonatal care have proven to be a
godsend for those suffering from the
extremely rare skin condition known as
Harlequin type exposes this disease is
distinguished by the presence of a thick
hard armor-like plate of dry skin all
over the body dehydration and
respiratory issues are common as is
serious infection due to the skins
cracked arid nature this disease was
almost always fatal to infants when it
was first seen during the mid 1700s
today however early care and treatment
means that babies born with Harlequin
type XP osis now have a fighting chance
for survival when I get such ignorant
sand things it does chip away and I just
hope it doesn’t completely take take my
confidence away number four congenital
analgesia we’ve all day dreamed about
being a superhero and being able to
withstand an enormous amount of pain or
damage without batting an eye could you
do this harder what would happen if we
actually couldn’t feel any pain
whatsoever what this really be a good
thing not according to those who suffer
from congenital analgesia a rare and
dangerous disorder which does just that
it affects the body’s ability to feel
pain doctors believe an excessive amount
of endorphins produced in the brain
caused this condition unfortunately this
exacerbates damage to the body rather
than diminishing it many of those
afflicted by CA have reported biting off
their own tongue breaking bones or
suffering severe in
action number three ahlstrom syndrome
Ostrom syndrome or ahlstrom halgren
syndrome as it’s sometimes known is one
of the most recently discovered
conditions on our list first reported in
1959 by Swedish psychiatrist Carl Henry
Ostrom it’s also one of the rarest
conditions with just over 500 cases
having been reported all over the world
ahlstrom syndrome can usually be seen in
infancy characterized by a wide array of
severe organ issues obesity blindness
loss of hearing and diabetes are just a
few of the symptoms associated with AF
if you live past age 50 due largely to
the fact that there’s currently no cure
for the disease only therapy and
treatment number two fields disease no
medical condition is rarer than the
neuromuscular condition known as Fields
disease only two cases have been
reported to date the twin sisters
Catherine and Kirsty fields for whom the
disease is named in 1998 their parents
noticed some initial problems within
five years the girls were suffering from
severe muscular degeneration eventually
losing their ability to speak and
requiring Walker’s to assist in mobility
meanwhile neurological issues caused
severe shaking and trembling hands so
difficult to manage a 2012 update from
Britain’s Daily Mirror showed the girls
in good spirits after they were given
speech devices similar to those used by
Stephen Hawking before we named our
rarest medical conditions here are some
honorable mentions
[Music]
number one aquagenic urticaria some
people can’t swim some folks just hate
the water water never touch the stuff
fish in it but what if exposure to h2o
actually caused you intense physical
pain
those who suffer from aquagenic
urticaria an intense skin reaction to
water contend with this problem on a
daily basis red itchy hives can emerge
on the skin only minutes after exposure
what’s more there’s no cure for
aquagenic urticaria which is more likely
to occur in women than men only
antihistamine steroids radiation or
medication offer limited comfort to
those for whom every shower or hand
washing session is a challenge do you
agree with our pics check out these
other great clips from WatchMojo and
subscribe for new videos every day
[Music]
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