hello everyone you know embellishments
I’ve been thinking about inviting these guys to my place
at a lecture
hundred percent attendance
guaranteed here me organizers
marked with wires and said that now
I am part of the collective mind
that is, we have one brain and one part of Matt
brain that is I wanted to ask you
you know, this is a self-portrait
van gogh vincent van gogh
umnichki which Pablo Picasso
but this guy you know exactly Harrison
Ford Hollywood actor you know that
common between all these people they were
sick
depression now is very
approximately 109 with this
the diagnosis of depression is about 350
million people and the cost of treatment
care for these patients is costly
about 200 10 billion dollars a year
by the World Organization
health depression in 2020
will be in second place for
disability that is, it is a disease disease
centuries
illness of our society and here it is interesting
but that the world organization
health research rule
some countries as much
prevalence of depression among
how do you think which country
was in first place by number
a surprisingly sunny side
France in France every fifth
diagnose the adult population
is diagnosed with depression and you know
there is one country in which until 2000
there was not a single depressed patient
who calls the country no China
and not because it is a communist
country and everyone is happy within the framework of
Chinese culture is not depressed
disease is a feature of personality from
2000 when the Chinese began to apply
criteria of depression among themselves
patients
they immediately got depressed on
still it is somewhere around 9 percent
here are some interesting facts
number of depressed patients constantly
Growth and we have very serious
Problems
look at this slide and on these figures
50 percent of the patients we simply do not have
is diagnosed
why because not when the patient is not
will complain that I feel
unhappy or
I have a bad mood or I have
lost the meaning of life he is not sick
considers it as a symptom of the disease and the doctor does not
is able to diagnose
moreover , we do not have any
laboratory analysis, we can take
blood make a blood test
But this does not help us diagnose
depression depression depression diagnosis
is based on a dialogue between
sick and doctor
what condition is necessary for this though
would one of them be healthy
which is not always the case
further for the treatment of patients with depression we
use drugs called
antidepressants unfortunately action
antidepressants
develops slowly somewhere in the second
month of continuous intake of these drugs
the patient begins to feel that something
changes for the better during this period
patients experience only secondary
effects of these drugs before the onset
therapeutic action and 50 percent of them
throw medication during the first
weeks after the start of treatment, moreover
take a look at the last sentence
in 30 40 percent of patients these drugs
just does not work and it’s big
a big problem but for many years
scientists were searching
molecules of happiness that is, they thought that here
lack of some molecule in the brain and
is the cause of depression
These searches have not been successful because
that the principle of the work of our brain is built
on networks on neural networks where
millions of nerve cells
network and in the work of this network
hundreds of thousands and molecules are involved and
some of these molecules or
several
can lead to such an effect therefore
I can say that to date
I know neither the reasons nor the mechanisms of this
diseases
but there are a lot of interesting theories
and here’s one of these theory I want
or both about this theory I want you
tell sometime 55 to 65 year
this guy was a learned martin
Seligman he conducted experiments on dogs
he put the dog in the cage now these
Experiments are prohibited because ethical
considerations do not allow the use of
dogs in such experiments and missed it
through the floor of the cell electric current
a weak electric current is enough
unpleasant for the dog and so he did in
for five to six days, then on the seventh
day he put the animal in this cage
also has a painful effect on you
but the door to this cage
remained open and this gave
the ability of a dog to escape this
unpleasant feeling that it turned out that
80 percent of dogs really ran away
from this unpleasant cell to 20
percent
remained in it that is they agreed
on this for this pain he called it flax as
you demolished what is translated in Estonian
language then buy here this bit to save here
both ace or it’s common helplessness yes
but I wrote my article
animals are unhappy
a few years later
there was a theory that at the basis of
and prissy lies here this
formulation is the formation of
sustainable negative schemes
which are fixed in the mask due to
insufficient plasticity of the brain
a person is trained to be unhappy but in
The same time the plasticity of the brain does not
allows him
To re-learn and become happy is very
interesting theory
Look, after all, our brain is very
stable and it must be stable
he must remember
he must remember the information he
must remember the skills he is only in
This is based on its stability but
the same time the brain receives
but groups are bombarded with a huge flow
information visual verbal he
he he sees he is constantly
under stress and this stability can
be made so
due to its plasticity
in the absence of plasticity, this
information flow this bombardment
can destroy asmus plasticity of the brain
it is necessary for training and this is also
necessary and for retraining
striking plasticity of the brain
observed in children a year-old baby
can teach a thousand times more than
they have an amazing adult
plastic
this plasticity for the ability
the small structure responds
a brain that is called and on campus
hippocampus this translation means
sea horse really if he
It is highlighted here that he shows the brain and
see the yellow color and that’s how it looks
this structure is indeed
it resembles a sea horse and what are you doing
This structure needs this
the structure responded in favor of
the formation of memory and this information
which is the basis of the memory
is in this structure for
two weeks
then it is sent to other departments
brain and pack cleaned old
information and able again
perceive new information and
this structure
you found that this is the only or
may be one of the few places in the brain
where the formation of new
nerve cells is a process called
neurogenesis, this neurogenesis was found
not only there in children
he was also found in the adult brain
somewhere in the day
there are added 600 to 800
nerve cells and they are in the ranks become
nerve cells are built in early for me
network and are able to perceive a new
information the ability to retrain
and this neurogenesis is shown by this
we can see these in blue
new cells are shown
that it was discovered that the slaughter
Number of new suicides
cells is reduced
patients with severe
psychological trauma, the number of these
cells reduced less
neurons are born in this structure and
scientists have suggested that this lies in the
basis
depression arose the question and what about how
we can affect the plasticity
the hippocampus and this neurogenesis, and
Here, too, is the rapier of the cabin
reduction of neurogenesis can live in
The basis of depression I want to show you
one slide please pay attention
we are able
color these new cells that
born in the hippocampus
For example, here black color is shown and
near red that’s these reds
dots are a newborn nerve cell
and here are compared
this neurogenesis in control and early
runner who runs
the physical load that we see
see how the quantity has changed
these new cells
is exercise is very
healthy stimulates neurogenesis the same
most
turned out to have an effect
antidepressant fluoxetine prose he too
increased or increased the number of new
cells
What else contributes to the fascination of these
cells
enriched environment of toys
the child bears this load on himself
they stimulate the child’s neurogenesis that
adult can encourage that
an adult can be enriched by an external
the environment
travel is also
neuron-enriched environment interesting
a study was conducted on drivers
taxis that must be constantly
remember to navigate and
it turned out that the volume of the hippocampus
taxi drivers are much more than
average for a population in a London taxi
The publication was very interesting in
anyway
next I want to show you this slide
maybe I’ll get a video
the organizers of this conference here
shows the baby young mothers who have
money will return this age you
noticed how they walk
who they are not gnu
Do not walk like some of the themes they are jumping
I have three grandchildren, they all say no one
I do not walk normally and I often hear
mamba that you jump for the sake of normal
never say
this is what your children are like
It is a search path that does not contribute to
rogen and after in the hippocampus
this is an interesting thing that is discovered
sex most recently
that is children jumping brain sends them
jump signal
and by jumping they improve the plasticity of the brain
it’s very cool I like children here
so she went to see to
[applause]
class I do not jump so let’s go
then look here I am
showed I show this a few
things that improve our plasticity
brain and the ability of our brain
retraining
and here this physical activity
this trip is antidepressants
when it is necessary but immediately arises
question, why, then, are all on at the
patients
sometimes does not work see you see us
these are the things that we give
brain perry learn but perry learn
a man must himself, in fact, everything is
that we know we did not learn
professors are not teachers in the school teacher
everyone spoils everything
not on not make us learn to learn we
should themselves, but these things they need us
just give us the opportunity to open
the door to this retraining is such
things I wanted to tell you today
Thank you for attention
[applause]
I’ve been thinking about inviting these guys to my place
at a lecture
hundred percent attendance
guaranteed here me organizers
marked with wires and said that now
I am part of the collective mind
that is, we have one brain and one part of Matt
brain that is I wanted to ask you
you know, this is a self-portrait
van gogh vincent van gogh
umnichki which Pablo Picasso
but this guy you know exactly Harrison
Ford Hollywood actor you know that
common between all these people they were
sick
depression now is very
approximately 109 with this
the diagnosis of depression is about 350
million people and the cost of treatment
care for these patients is costly
about 200 10 billion dollars a year
by the World Organization
health depression in 2020
will be in second place for
disability that is, it is a disease disease
centuries
illness of our society and here it is interesting
but that the world organization
health research rule
some countries as much
prevalence of depression among
how do you think which country
was in first place by number
a surprisingly sunny side
France in France every fifth
diagnose the adult population
is diagnosed with depression and you know
there is one country in which until 2000
there was not a single depressed patient
who calls the country no China
and not because it is a communist
country and everyone is happy within the framework of
Chinese culture is not depressed
disease is a feature of personality from
2000 when the Chinese began to apply
criteria of depression among themselves
patients
they immediately got depressed on
still it is somewhere around 9 percent
here are some interesting facts
number of depressed patients constantly
Growth and we have very serious
Problems
look at this slide and on these figures
50 percent of the patients we simply do not have
is diagnosed
why because not when the patient is not
will complain that I feel
unhappy or
I have a bad mood or I have
lost the meaning of life he is not sick
considers it as a symptom of the disease and the doctor does not
is able to diagnose
moreover , we do not have any
laboratory analysis, we can take
blood make a blood test
But this does not help us diagnose
depression depression depression diagnosis
is based on a dialogue between
sick and doctor
what condition is necessary for this though
would one of them be healthy
which is not always the case
further for the treatment of patients with depression we
use drugs called
antidepressants unfortunately action
antidepressants
develops slowly somewhere in the second
month of continuous intake of these drugs
the patient begins to feel that something
changes for the better during this period
patients experience only secondary
effects of these drugs before the onset
therapeutic action and 50 percent of them
throw medication during the first
weeks after the start of treatment, moreover
take a look at the last sentence
in 30 40 percent of patients these drugs
just does not work and it’s big
a big problem but for many years
scientists were searching
molecules of happiness that is, they thought that here
lack of some molecule in the brain and
is the cause of depression
These searches have not been successful because
that the principle of the work of our brain is built
on networks on neural networks where
millions of nerve cells
network and in the work of this network
hundreds of thousands and molecules are involved and
some of these molecules or
several
can lead to such an effect therefore
I can say that to date
I know neither the reasons nor the mechanisms of this
diseases
but there are a lot of interesting theories
and here’s one of these theory I want
or both about this theory I want you
tell sometime 55 to 65 year
this guy was a learned martin
Seligman he conducted experiments on dogs
he put the dog in the cage now these
Experiments are prohibited because ethical
considerations do not allow the use of
dogs in such experiments and missed it
through the floor of the cell electric current
a weak electric current is enough
unpleasant for the dog and so he did in
for five to six days, then on the seventh
day he put the animal in this cage
also has a painful effect on you
but the door to this cage
remained open and this gave
the ability of a dog to escape this
unpleasant feeling that it turned out that
80 percent of dogs really ran away
from this unpleasant cell to 20
percent
remained in it that is they agreed
on this for this pain he called it flax as
you demolished what is translated in Estonian
language then buy here this bit to save here
both ace or it’s common helplessness yes
but I wrote my article
animals are unhappy
a few years later
there was a theory that at the basis of
and prissy lies here this
formulation is the formation of
sustainable negative schemes
which are fixed in the mask due to
insufficient plasticity of the brain
a person is trained to be unhappy but in
The same time the plasticity of the brain does not
allows him
To re-learn and become happy is very
interesting theory
Look, after all, our brain is very
stable and it must be stable
he must remember
he must remember the information he
must remember the skills he is only in
This is based on its stability but
the same time the brain receives
but groups are bombarded with a huge flow
information visual verbal he
he he sees he is constantly
under stress and this stability can
be made so
due to its plasticity
in the absence of plasticity, this
information flow this bombardment
can destroy asmus plasticity of the brain
it is necessary for training and this is also
necessary and for retraining
striking plasticity of the brain
observed in children a year-old baby
can teach a thousand times more than
they have an amazing adult
plastic
this plasticity for the ability
the small structure responds
a brain that is called and on campus
hippocampus this translation means
sea horse really if he
It is highlighted here that he shows the brain and
see the yellow color and that’s how it looks
this structure is indeed
it resembles a sea horse and what are you doing
This structure needs this
the structure responded in favor of
the formation of memory and this information
which is the basis of the memory
is in this structure for
two weeks
then it is sent to other departments
brain and pack cleaned old
information and able again
perceive new information and
this structure
you found that this is the only or
may be one of the few places in the brain
where the formation of new
nerve cells is a process called
neurogenesis, this neurogenesis was found
not only there in children
he was also found in the adult brain
somewhere in the day
there are added 600 to 800
nerve cells and they are in the ranks become
nerve cells are built in early for me
network and are able to perceive a new
information the ability to retrain
and this neurogenesis is shown by this
we can see these in blue
new cells are shown
that it was discovered that the slaughter
Number of new suicides
cells is reduced
patients with severe
psychological trauma, the number of these
cells reduced less
neurons are born in this structure and
scientists have suggested that this lies in the
basis
depression arose the question and what about how
we can affect the plasticity
the hippocampus and this neurogenesis, and
Here, too, is the rapier of the cabin
reduction of neurogenesis can live in
The basis of depression I want to show you
one slide please pay attention
we are able
color these new cells that
born in the hippocampus
For example, here black color is shown and
near red that’s these reds
dots are a newborn nerve cell
and here are compared
this neurogenesis in control and early
runner who runs
the physical load that we see
see how the quantity has changed
these new cells
is exercise is very
healthy stimulates neurogenesis the same
most
turned out to have an effect
antidepressant fluoxetine prose he too
increased or increased the number of new
cells
What else contributes to the fascination of these
cells
enriched environment of toys
the child bears this load on himself
they stimulate the child’s neurogenesis that
adult can encourage that
an adult can be enriched by an external
the environment
travel is also
neuron-enriched environment interesting
a study was conducted on drivers
taxis that must be constantly
remember to navigate and
it turned out that the volume of the hippocampus
taxi drivers are much more than
average for a population in a London taxi
The publication was very interesting in
anyway
next I want to show you this slide
maybe I’ll get a video
the organizers of this conference here
shows the baby young mothers who have
money will return this age you
noticed how they walk
who they are not gnu
Do not walk like some of the themes they are jumping
I have three grandchildren, they all say no one
I do not walk normally and I often hear
mamba that you jump for the sake of normal
never say
this is what your children are like
It is a search path that does not contribute to
rogen and after in the hippocampus
this is an interesting thing that is discovered
sex most recently
that is children jumping brain sends them
jump signal
and by jumping they improve the plasticity of the brain
it’s very cool I like children here
so she went to see to
[applause]
class I do not jump so let’s go
then look here I am
showed I show this a few
things that improve our plasticity
brain and the ability of our brain
retraining
and here this physical activity
this trip is antidepressants
when it is necessary but immediately arises
question, why, then, are all on at the
patients
sometimes does not work see you see us
these are the things that we give
brain perry learn but perry learn
a man must himself, in fact, everything is
that we know we did not learn
professors are not teachers in the school teacher
everyone spoils everything
not on not make us learn to learn we
should themselves, but these things they need us
just give us the opportunity to open
the door to this retraining is such
things I wanted to tell you today
Thank you for attention
[applause]
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