let’s go up
thanks but those spontaneous applause
that have come out of the heart like that
thanks 9th bout having in 2012 a
patient that we will call jon because his
authentic identity is protected was
admitted to the wexner hospital of the
ohio state university afflicted by
bacterial pneumonia a very disease
common those who have passed us the
we have cured simply with
antibiotics but pneumonia de jong
it was different he did not react to the
common antibiotics and had advanced
so much that he had put Jon’s life in
critical risk plus I was not a
common patient from 2006 to 90
had been the people who presented
the same clinical picture of jong all
they had been attacked by super
bacteria that are not bacteria and
the underpants on the outside are not
bacteria that are capable of resisting
the antibiotics that previously killed them and
the truth is that it is a serious situation
every year they die in the world because of
superbug 700,000 people that’s
the population of all seville
Moreover charming so the
Nerd watch hospital medical team
ohio decided to take action and with
johnny used colistina a
very special antibiotic an antibiotic
extraordinary a last antibiotic
resource antibiotics that can only
used in case of life or death and that
luckily both for them and for
the other 90 patients could save them
the life
resolved issue charges me a tie of c’s
in a minute
in just three years they appeared in a
pig farm in china that are already
want to look for super bacteria there
able to resist colistin that
antibiotic of last resort that was
being the only option for patients
seizure was today in check
by bacteria that lived in pigs
and you will say good in pigs pigs and
humans are different species one
have your doubts on the bus in hour
tip but not the bacteria that affect
the pigs can not infect the
humans we can be calm then in
2016 in the USA a patient appeared with
urinary infection that was being
attacked by super resistant bacteria
to colistin the same resistance as
had appeared in the bacteria sows
all in danger what is happening
here we are going to fray this mystery
to understand what is happening
and let’s start with the bacteria
pathogenic because it seems that we have
lost the fear of bacteria true
an infection in a tooth an infection
in one ear and we are not afraid us
we are going to heal but it is that before the
arrival of antibiotics the
bacterial infections such as cavities
or pneumonia were able to kill
millions of people each year taking away
especially in children the situation
it’s really serious it was priming
especially children but luckily
with the arrival of antibiotics the
thing changed especially in the countries
enriched because with the treatments
with antibiotics we started to maintain
controlled to the bacteria but the
bacteria throughout evolution have
developed tools for
protect yourself from those antibiotics this is
basic biology random mutations in the
DNA in the genes of an individual
they produce changes in their characteristics
or even the acquisition of new
functions if a bacterium accumulates
changes in your genome in your DNA that
They allow surviving an antibiotic
turns into a super clear bacteria
yes
besides the super bacteria are very
altruistic unlike our class
policy they are to share
share everything they generate and
they share those resistance genes
bacterial especially of course with
their offspring but they are also capable
to do it horizontally if a
Adult bacterium meets another
adult bacteria even if they are species
different are able to transfer
genetic material like those genes from
antibiotic resistance through a
process called conjugation summarizing
for a bacterium to accumulate changes in
your genome in your DNA is capable of
resist an antibiotic becoming
well in super bacteria and can share
those resistance genes with other
bacteria should come into contact with
non-lethal doses of antibiotic
and that when it happens then when we go to
doctor prescribes us antibiotics and we do not
we finish the box we are giving doses no
lethal antibiotics to bacteria
that have infected us or when we have
a sore throat a flu or us
we go for the pin and without going to the doctor
We decided to take the antibiotics if the
ailment that we have our produced
by bacteria plus we’re not leaving
to heal, we are contacting
the non-pathogenic bacteria of our
bacterial flora with that antibiotic that
we are taking those bacteria
they can learn to resist that
antibiotic come into contact with other
pathogenic bacteria entering
our organism later on
it produces conjugation we spin leopard there
a second way of putting the
bacteria in contact with doses not
lethal antibiotics that have a lot
to do with Chinese pigs and that is
the antibiotics
fatten that the ranchers know and what
They use Spain is the fifth country in
world in the use of antibiotics
only for fattening we are also
raising pigs in pigs and
all farm animals on farms
intensive in hygienic conditions
really bad clear are getting
very sick to avoid those
diseases we are giving them
antibiotics preventively in the
I think it ‘s like they were going to ban
come without mercy and what happens we are
generating suitable spaces for
production of superbugs a
superbug produced in pigs in
the farm animals can get
up to our organism through the
foods
there to meet a bacterium
human pathogen and tell me you
we are screwed but but the beings
We have an ace up our sleeve
antibiotics of last resort for
prevent bacteria from entering
contact with all the antibiotics that
we have created a reservoir of
these molecules that we can only
use in hospitals before
deadly infections and when the others
treatments have failed colistin
what we use with jon is a
antibiotic of last resort but as
fattening that gives taste it prevents a
lot of diseases
the Chinese started giving it to the
pigs that was no idea true in so
only one year they developed super
bacteria in those pigs that resisted
colistina came in contact with
human pathogenic bacteria
there was conjugation and in the USA a patient
it could not be cured with colistin the
situation is so serious that the WHO
world health organization in a
2016 announcement warned us that in
brief we could enter the post era
antibiotic
an era in which common infections
small wounds could be again
potentially deadly and that in 2049
they can kill more than 10
millions of people a year even more
that cancer this far from being the
apocalyptic argument of a bad
series movie b is one of the
great challenges that we face
humanity in the 21st century
but not all bad news is the
tax money that is invested
in science is being well used the
that is invested in armament but good
let’s focus on the good because
for example in the institute scripts in
san diego in california are
developing a new antibiotic have
caught the active part of three
different antibiotics and they have put it together
in a single molecule so we have a
new antibiotic capable of killing
bacteria in three different ways
the first reproduction must avoid
be a bad person to do that but
good today against the super bacteria
anything goes
it reduces your metabolism too and in addition
is able to distort its wall
cell in this way if a bacterium
Learn to fight against one of these
three courses of action
the other two will end up eliminating the one
a bacteria learn to fight against
three courses of action at the same time is
highly unlikely this new
antibiotic is not yet ready for its
use in humans but opens a window of
hope in the fight against the super
bacteria we have a second formula
For example, do not use antibiotics
but use other things like use
non-pathogenic bacteria in the fight
against the bad for example this what
we are using in patients who have
intestinal infection we are giving them
non-pathogenic cells of the microbiota of
healthy people so we give
oral these bacteria reach the intestine
reproduce and expel displace the
pathogenic bacteria in medicine are
Technically known as a transplant
We have commonly called it stool
always eat the shit of others but
hey it looks like it’s working and every
there are more patients treated with this
kind of methodology but you see there
hope science works
against the clock to fight against
superbugs and if we support the
science of all the ways that we are
occur as fostering vocations
scientific in the youngest
investing making donations in
research projects or voting for
political parties that have policies
specific in research and
development we will be collaborating with
our own salvation that yes
no matter how much we develop science by
more that we have new antibiotics for
more than we use pathogenic bacteria
in our own benefit
if as individuals and as a species
we make responsible use of
our medications
we could be causing our
own destruction the fight against
Superbugs could be lost like this
that you have to pay attention to the doctor
time to take antibiotics we can
support with our purchases to those
companies that do not use antibiotics
way massively by looking at the
labels asking at the butcher shop
demanding a sensible production of the
meat that we eat only with the
combination of scientific development and
responsible use of our resources
we will be able to relegate the dreaded
it was post antibiotics to the stories of
science fiction
[Applause]
thanks but those spontaneous applause
that have come out of the heart like that
thanks 9th bout having in 2012 a
patient that we will call jon because his
authentic identity is protected was
admitted to the wexner hospital of the
ohio state university afflicted by
bacterial pneumonia a very disease
common those who have passed us the
we have cured simply with
antibiotics but pneumonia de jong
it was different he did not react to the
common antibiotics and had advanced
so much that he had put Jon’s life in
critical risk plus I was not a
common patient from 2006 to 90
had been the people who presented
the same clinical picture of jong all
they had been attacked by super
bacteria that are not bacteria and
the underpants on the outside are not
bacteria that are capable of resisting
the antibiotics that previously killed them and
the truth is that it is a serious situation
every year they die in the world because of
superbug 700,000 people that’s
the population of all seville
Moreover charming so the
Nerd watch hospital medical team
ohio decided to take action and with
johnny used colistina a
very special antibiotic an antibiotic
extraordinary a last antibiotic
resource antibiotics that can only
used in case of life or death and that
luckily both for them and for
the other 90 patients could save them
the life
resolved issue charges me a tie of c’s
in a minute
in just three years they appeared in a
pig farm in china that are already
want to look for super bacteria there
able to resist colistin that
antibiotic of last resort that was
being the only option for patients
seizure was today in check
by bacteria that lived in pigs
and you will say good in pigs pigs and
humans are different species one
have your doubts on the bus in hour
tip but not the bacteria that affect
the pigs can not infect the
humans we can be calm then in
2016 in the USA a patient appeared with
urinary infection that was being
attacked by super resistant bacteria
to colistin the same resistance as
had appeared in the bacteria sows
all in danger what is happening
here we are going to fray this mystery
to understand what is happening
and let’s start with the bacteria
pathogenic because it seems that we have
lost the fear of bacteria true
an infection in a tooth an infection
in one ear and we are not afraid us
we are going to heal but it is that before the
arrival of antibiotics the
bacterial infections such as cavities
or pneumonia were able to kill
millions of people each year taking away
especially in children the situation
it’s really serious it was priming
especially children but luckily
with the arrival of antibiotics the
thing changed especially in the countries
enriched because with the treatments
with antibiotics we started to maintain
controlled to the bacteria but the
bacteria throughout evolution have
developed tools for
protect yourself from those antibiotics this is
basic biology random mutations in the
DNA in the genes of an individual
they produce changes in their characteristics
or even the acquisition of new
functions if a bacterium accumulates
changes in your genome in your DNA that
They allow surviving an antibiotic
turns into a super clear bacteria
yes
besides the super bacteria are very
altruistic unlike our class
policy they are to share
share everything they generate and
they share those resistance genes
bacterial especially of course with
their offspring but they are also capable
to do it horizontally if a
Adult bacterium meets another
adult bacteria even if they are species
different are able to transfer
genetic material like those genes from
antibiotic resistance through a
process called conjugation summarizing
for a bacterium to accumulate changes in
your genome in your DNA is capable of
resist an antibiotic becoming
well in super bacteria and can share
those resistance genes with other
bacteria should come into contact with
non-lethal doses of antibiotic
and that when it happens then when we go to
doctor prescribes us antibiotics and we do not
we finish the box we are giving doses no
lethal antibiotics to bacteria
that have infected us or when we have
a sore throat a flu or us
we go for the pin and without going to the doctor
We decided to take the antibiotics if the
ailment that we have our produced
by bacteria plus we’re not leaving
to heal, we are contacting
the non-pathogenic bacteria of our
bacterial flora with that antibiotic that
we are taking those bacteria
they can learn to resist that
antibiotic come into contact with other
pathogenic bacteria entering
our organism later on
it produces conjugation we spin leopard there
a second way of putting the
bacteria in contact with doses not
lethal antibiotics that have a lot
to do with Chinese pigs and that is
the antibiotics
fatten that the ranchers know and what
They use Spain is the fifth country in
world in the use of antibiotics
only for fattening we are also
raising pigs in pigs and
all farm animals on farms
intensive in hygienic conditions
really bad clear are getting
very sick to avoid those
diseases we are giving them
antibiotics preventively in the
I think it ‘s like they were going to ban
come without mercy and what happens we are
generating suitable spaces for
production of superbugs a
superbug produced in pigs in
the farm animals can get
up to our organism through the
foods
there to meet a bacterium
human pathogen and tell me you
we are screwed but but the beings
We have an ace up our sleeve
antibiotics of last resort for
prevent bacteria from entering
contact with all the antibiotics that
we have created a reservoir of
these molecules that we can only
use in hospitals before
deadly infections and when the others
treatments have failed colistin
what we use with jon is a
antibiotic of last resort but as
fattening that gives taste it prevents a
lot of diseases
the Chinese started giving it to the
pigs that was no idea true in so
only one year they developed super
bacteria in those pigs that resisted
colistina came in contact with
human pathogenic bacteria
there was conjugation and in the USA a patient
it could not be cured with colistin the
situation is so serious that the WHO
world health organization in a
2016 announcement warned us that in
brief we could enter the post era
antibiotic
an era in which common infections
small wounds could be again
potentially deadly and that in 2049
they can kill more than 10
millions of people a year even more
that cancer this far from being the
apocalyptic argument of a bad
series movie b is one of the
great challenges that we face
humanity in the 21st century
but not all bad news is the
tax money that is invested
in science is being well used the
that is invested in armament but good
let’s focus on the good because
for example in the institute scripts in
san diego in california are
developing a new antibiotic have
caught the active part of three
different antibiotics and they have put it together
in a single molecule so we have a
new antibiotic capable of killing
bacteria in three different ways
the first reproduction must avoid
be a bad person to do that but
good today against the super bacteria
anything goes
it reduces your metabolism too and in addition
is able to distort its wall
cell in this way if a bacterium
Learn to fight against one of these
three courses of action
the other two will end up eliminating the one
a bacteria learn to fight against
three courses of action at the same time is
highly unlikely this new
antibiotic is not yet ready for its
use in humans but opens a window of
hope in the fight against the super
bacteria we have a second formula
For example, do not use antibiotics
but use other things like use
non-pathogenic bacteria in the fight
against the bad for example this what
we are using in patients who have
intestinal infection we are giving them
non-pathogenic cells of the microbiota of
healthy people so we give
oral these bacteria reach the intestine
reproduce and expel displace the
pathogenic bacteria in medicine are
Technically known as a transplant
We have commonly called it stool
always eat the shit of others but
hey it looks like it’s working and every
there are more patients treated with this
kind of methodology but you see there
hope science works
against the clock to fight against
superbugs and if we support the
science of all the ways that we are
occur as fostering vocations
scientific in the youngest
investing making donations in
research projects or voting for
political parties that have policies
specific in research and
development we will be collaborating with
our own salvation that yes
no matter how much we develop science by
more that we have new antibiotics for
more than we use pathogenic bacteria
in our own benefit
if as individuals and as a species
we make responsible use of
our medications
we could be causing our
own destruction the fight against
Superbugs could be lost like this
that you have to pay attention to the doctor
time to take antibiotics we can
support with our purchases to those
companies that do not use antibiotics
way massively by looking at the
labels asking at the butcher shop
demanding a sensible production of the
meat that we eat only with the
combination of scientific development and
responsible use of our resources
we will be able to relegate the dreaded
it was post antibiotics to the stories of
science fiction
[Applause]
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