[Music]
[Music]
there is something you know fair in life
is aging because whether you’re poor or
you’re rich we all age one day at the
time and the thing that we all have in
common is nobody wants to age so what
I’m going to be presenting today is the
research that we have been doing to try
to delay aging so if you want to hear
about this you have to give me a big yes
okay right on so here is what I’m gonna
try to show you is you know here we have
a young individuals and a whole
individuals and what’s happen is you
know when we’re young we have a lot of
stem cells and those stem cells are very
active there really is a lot of factors
and this is why our kids feel very fast
when they injure themselves when we get
older we have less stem cells and those
stem cells are not very active so this
is why you know we’re not repairing our
tissue very well so what we’re trying to
do here is not to take someone order to
make him younger is to take someone
older and make him hate out here so here
is you know what we have been doing so
you probably have seen you know this on
TV you know those proteinuria patient
you know they are like 10 years of age
and they look like 85 years of age age
very fast sure enough we made a
transgenic mice here this mice you know
as a same mutation gene mutation at the
pro Tyria patient and this mice age very
fast as well this mice you know leave
only 21 days normal mice will leave two
years so what we ask is we found that
the stem cell from those mice you know
get depleted very fast so what we ask is
if we inject young stem cell to those
mice can we make them leave with longer
than 21 days and here this is what’s
happened you can see that my the red bar
here the mice injected with all stem
cells you can see now they live for up
to 70 days not only do you live longer
but they look better too so I don’t know
if a mice can look better but those
might look better than a non injected
mice so the bottom line here is what we
found is those protein your minds if you
inject young stem cells you can make
them live longer
and you know they look LT or as well so
what doesn’t mean for all of us today so
that mean that the best gift we can give
to our newborn is to Bhangarh stem cells
at Birth from the umbilical cord you can
bang their stem cells and after this
those cells you know again we can Orvis
the stem cells we can grow millions of
them and what we’re going to do is we’re
gonna Bank them as soon as we put them
we freeze them up those cells stop the
aging 20 years later they come in Vail
and this key and they injure themselves
then we can tow those cells put this in
a syringe and basically treat them and
again not only after injuries but maybe
you know we can if the they look older a
little bit so maybe we can inject their
stem cells to delay their aging process
the same thing is true for all the
soldiers just think about you know if we
were able to do this with all the
soldiers we are a vessel stem cell
before they go to the battlefield and
what’s happened is you know if they have
an injury they come back so we have stem
cell to treat them think about those
astronauts they go on the moon they face
radiation so our vesting our stem so
before they go in a shuttle they come
back then we have their stem cell to
treat them so this is really preventive
medicine I know what you’re thinking
though you’re probably thinking we’re –
were to hold for this because you know
we’re not taking at birth here so what
we did is you know we has a question you
know many people tell me you know I am
way to hold to get my stem cells Bank
you’re never to hold for that because
let me give you an example if at Birth
you know let’s say that all your stem
cells are good at 50 years of age let’s
say that 50% of them are very good at 75
maybe 25% of them are very good so what
when we do the banking we can identify
the good stem cells and this is the one
that we grow millions of them but you
will tell me you know what’s happen
what’s happened with the one that are
not so good so we did a lot of research
recently and we found that you know we
find a way to take a whole stem cells to
make them young again and I’m gonna go
in details a little bit here you know in
in genetics but the bottom line here we
found that when a young stem cells get
old we have a protein complex they’re
called mTOR and this protein complex
sticker yarns themselves and make them
hold why is that important for us
because we find draw
we were looking for drug that can block
dissent or pathways and it turns out
that one of the drug here is rapamycin
rapamycin is an FDA approved drug it’s
an immunosuppressive Asian and rapamycin
is able to block the enter and proven
your stem cells to get old and sure
enough now people are using rapamycin
here we have done some studies in rat in
mice when you give them rapamycin they
live longer they live out here and now
you have people that take Reformation
because an FDA approved drug already
they have side effects associated with
it but you know your doctor can decide
not only that but another drug year this
drug here you know it’s a diabetic drug
metformin metformin has been used to
delay aging for many years now this is a
drug the cause of it is almost nothing
and these drugs appear to be very good
to delay aging as well so now I’m going
to move to the next point we have done a
lot of science to try to understand
where the stem cell comes from because
you have stem cells in your liver you
have stem cells a new fat in your bone
marrow in your muscle so it turns out
that we found that stem cells come from
the blood vessels all the micro vessel
that you have in your tissues the
systems that come from and why is that
important because if I can increase the
number of blood vessel I should be able
to increase the number of stem cells and
the best way to increase the number of
blood vessels folks is exercise because
when you do exercise you increase the
number but vessels in your brain in your
heart in your muscle and sure enough we
wanted to prove it right
we put my son treadmill mice are very
lazy in nature mice they hit the drink
they sleep those won’t do not those
won’t run but sure enough you know when
we run them and after this if we enjoyed
our muscle their body heal significantly
faster than the mice that are sitting in
their cage doing nothing and I just
would like to say that some experiment
has been done recently
instead of engineering those mice that
were running the inject cancer cells to
those mice all the mice that were
sitting in their box not running you
know they all died from that tumor which
is expected 50% of the mice that were
running survived that term so again
folks exercise is very good for you so
now you know and again you know timing
is everything you know this issue of
time
you know that was published last year
you need to get that issue but it is
very important they assured that you
know research link to exercise to less
depression better memory quicker
learning you know if you took the other
side you can keep yourself younger and
sure enough exercise has been shown to
extend lifespan you know by as much as
five years
so again exercise is very important so
now I just would like to finish by
saying that not only your stem cells get
hold when you get holder your blood get
hold as well and what we have done here
you’re gonna find this a little bit
funny but what we take we take a two
mice and we stitch them together
stitchers
their skin together and what we found if
you stitch a young mice to a whole
night’s ok you can rejuvenate the whole
minds the whole mice with the young
blood from the young mice now the young
the whole my snout can repair our muscle
there are bone they’re hard better
showing clearly that the young blood can
rejuvenate the whole minds so maybe
after all you know not only we need to
bank your stem cells we may need to Bank
your blood as well because your blood is
maybe something we can use on the road
down the road and finally this is my
best part here do you know that women
live longer than men yeah I know the
woman or laughing the man or like are
you crazy or what woman live longer than
men in the on average in United States
woman live on average 80 years old
the man is 74 why woman live longer than
men people will tell you well men were
crazy okay we secrete testosterone we
take risk taking I went skiing this
morning I went downhill but this is not
the reason why women live longer than
men folks you know why because if you
take mice if you take rat if you take
rabbits the female always ought leave
the male and they don’t ski and they
don’t bite they don’t do any of that so
clearly there is something more biologic
about that about why women live longer
than men and we think that this is you
know when the mud when the woman is
pregnant she’s connected to her fetus
and the fetus is the young and the woman
is hold older so the bottom line is you
have factor coming from the fetters that
held the model and again you know we
have done a study on this and we we we
as a question we said well if woman that
has never been pregnant on average
doesn’t live longer than men suggesting
that maybe pregnancy play a role here’s
a paper showing that woman who has been
pregnant between the age of 40 to 50
years of age have extremely low Nativity
is in this paper the woman that they
were pulling in this paper you know
we’re living over 100 year old so again
you know maybe during pregnancy you
suffer but you’re getting a lot of
payback from the Vettes so I just would
like to say that you know even if we do
you know even if I discover a pills for
anti-aging or Bank your stem cells there
is a lot of thing is that only one shot
and we’re going to cure everything so we
believe that down the road we can become
your personal trainer for aging so we
can stem
Bank your stem cells we can also Bank
your blood we can give you on teaching
drugs we can exercise it’s very
important but too much is not good so
you have to exercise the right way
nutrition is very important folks but
also you know like I said to people you
have to work with us if I give you the
best drug to delay aging but you’re
dressing like you know 20 year older and
you are then you’re gonna look older so
I think you know all those thing
mediation yoga you know all player all
here too so I just would like to say
that maybe down the road we’re going to
become your personal trainer for LT
aging and I just would like to finish by
saying that science and heart can come
together at one point
so we know the word that down the road
maybe when you Bank your stem cells we
can make a very nice frame with your
home stem cells on it that you can
display in your house and when you’re
going to show this to your friend you
can say this is my stem cells here so
again you know I just would like to
finish by saying that you know you’re
probably noticed you know I’m Canadian
and everything that we do in Canada
relate to our tea so here is it good
occupy a place where the park is a great
occupier play where the park is
going to be so as scientists I can tell
you five five years from now seven year
from now you are going to have your stem
cells bank because that’s the right
thing to do so thank you very much for
your attention
[Applause]
[Music]
you
[Music]
there is something you know fair in life
is aging because whether you’re poor or
you’re rich we all age one day at the
time and the thing that we all have in
common is nobody wants to age so what
I’m going to be presenting today is the
research that we have been doing to try
to delay aging so if you want to hear
about this you have to give me a big yes
okay right on so here is what I’m gonna
try to show you is you know here we have
a young individuals and a whole
individuals and what’s happen is you
know when we’re young we have a lot of
stem cells and those stem cells are very
active there really is a lot of factors
and this is why our kids feel very fast
when they injure themselves when we get
older we have less stem cells and those
stem cells are not very active so this
is why you know we’re not repairing our
tissue very well so what we’re trying to
do here is not to take someone order to
make him younger is to take someone
older and make him hate out here so here
is you know what we have been doing so
you probably have seen you know this on
TV you know those proteinuria patient
you know they are like 10 years of age
and they look like 85 years of age age
very fast sure enough we made a
transgenic mice here this mice you know
as a same mutation gene mutation at the
pro Tyria patient and this mice age very
fast as well this mice you know leave
only 21 days normal mice will leave two
years so what we ask is we found that
the stem cell from those mice you know
get depleted very fast so what we ask is
if we inject young stem cell to those
mice can we make them leave with longer
than 21 days and here this is what’s
happened you can see that my the red bar
here the mice injected with all stem
cells you can see now they live for up
to 70 days not only do you live longer
but they look better too so I don’t know
if a mice can look better but those
might look better than a non injected
mice so the bottom line here is what we
found is those protein your minds if you
inject young stem cells you can make
them live longer
and you know they look LT or as well so
what doesn’t mean for all of us today so
that mean that the best gift we can give
to our newborn is to Bhangarh stem cells
at Birth from the umbilical cord you can
bang their stem cells and after this
those cells you know again we can Orvis
the stem cells we can grow millions of
them and what we’re going to do is we’re
gonna Bank them as soon as we put them
we freeze them up those cells stop the
aging 20 years later they come in Vail
and this key and they injure themselves
then we can tow those cells put this in
a syringe and basically treat them and
again not only after injuries but maybe
you know we can if the they look older a
little bit so maybe we can inject their
stem cells to delay their aging process
the same thing is true for all the
soldiers just think about you know if we
were able to do this with all the
soldiers we are a vessel stem cell
before they go to the battlefield and
what’s happened is you know if they have
an injury they come back so we have stem
cell to treat them think about those
astronauts they go on the moon they face
radiation so our vesting our stem so
before they go in a shuttle they come
back then we have their stem cell to
treat them so this is really preventive
medicine I know what you’re thinking
though you’re probably thinking we’re –
were to hold for this because you know
we’re not taking at birth here so what
we did is you know we has a question you
know many people tell me you know I am
way to hold to get my stem cells Bank
you’re never to hold for that because
let me give you an example if at Birth
you know let’s say that all your stem
cells are good at 50 years of age let’s
say that 50% of them are very good at 75
maybe 25% of them are very good so what
when we do the banking we can identify
the good stem cells and this is the one
that we grow millions of them but you
will tell me you know what’s happen
what’s happened with the one that are
not so good so we did a lot of research
recently and we found that you know we
find a way to take a whole stem cells to
make them young again and I’m gonna go
in details a little bit here you know in
in genetics but the bottom line here we
found that when a young stem cells get
old we have a protein complex they’re
called mTOR and this protein complex
sticker yarns themselves and make them
hold why is that important for us
because we find draw
we were looking for drug that can block
dissent or pathways and it turns out
that one of the drug here is rapamycin
rapamycin is an FDA approved drug it’s
an immunosuppressive Asian and rapamycin
is able to block the enter and proven
your stem cells to get old and sure
enough now people are using rapamycin
here we have done some studies in rat in
mice when you give them rapamycin they
live longer they live out here and now
you have people that take Reformation
because an FDA approved drug already
they have side effects associated with
it but you know your doctor can decide
not only that but another drug year this
drug here you know it’s a diabetic drug
metformin metformin has been used to
delay aging for many years now this is a
drug the cause of it is almost nothing
and these drugs appear to be very good
to delay aging as well so now I’m going
to move to the next point we have done a
lot of science to try to understand
where the stem cell comes from because
you have stem cells in your liver you
have stem cells a new fat in your bone
marrow in your muscle so it turns out
that we found that stem cells come from
the blood vessels all the micro vessel
that you have in your tissues the
systems that come from and why is that
important because if I can increase the
number of blood vessel I should be able
to increase the number of stem cells and
the best way to increase the number of
blood vessels folks is exercise because
when you do exercise you increase the
number but vessels in your brain in your
heart in your muscle and sure enough we
wanted to prove it right
we put my son treadmill mice are very
lazy in nature mice they hit the drink
they sleep those won’t do not those
won’t run but sure enough you know when
we run them and after this if we enjoyed
our muscle their body heal significantly
faster than the mice that are sitting in
their cage doing nothing and I just
would like to say that some experiment
has been done recently
instead of engineering those mice that
were running the inject cancer cells to
those mice all the mice that were
sitting in their box not running you
know they all died from that tumor which
is expected 50% of the mice that were
running survived that term so again
folks exercise is very good for you so
now you know and again you know timing
is everything you know this issue of
time
you know that was published last year
you need to get that issue but it is
very important they assured that you
know research link to exercise to less
depression better memory quicker
learning you know if you took the other
side you can keep yourself younger and
sure enough exercise has been shown to
extend lifespan you know by as much as
five years
so again exercise is very important so
now I just would like to finish by
saying that not only your stem cells get
hold when you get holder your blood get
hold as well and what we have done here
you’re gonna find this a little bit
funny but what we take we take a two
mice and we stitch them together
stitchers
their skin together and what we found if
you stitch a young mice to a whole
night’s ok you can rejuvenate the whole
minds the whole mice with the young
blood from the young mice now the young
the whole my snout can repair our muscle
there are bone they’re hard better
showing clearly that the young blood can
rejuvenate the whole minds so maybe
after all you know not only we need to
bank your stem cells we may need to Bank
your blood as well because your blood is
maybe something we can use on the road
down the road and finally this is my
best part here do you know that women
live longer than men yeah I know the
woman or laughing the man or like are
you crazy or what woman live longer than
men in the on average in United States
woman live on average 80 years old
the man is 74 why woman live longer than
men people will tell you well men were
crazy okay we secrete testosterone we
take risk taking I went skiing this
morning I went downhill but this is not
the reason why women live longer than
men folks you know why because if you
take mice if you take rat if you take
rabbits the female always ought leave
the male and they don’t ski and they
don’t bite they don’t do any of that so
clearly there is something more biologic
about that about why women live longer
than men and we think that this is you
know when the mud when the woman is
pregnant she’s connected to her fetus
and the fetus is the young and the woman
is hold older so the bottom line is you
have factor coming from the fetters that
held the model and again you know we
have done a study on this and we we we
as a question we said well if woman that
has never been pregnant on average
doesn’t live longer than men suggesting
that maybe pregnancy play a role here’s
a paper showing that woman who has been
pregnant between the age of 40 to 50
years of age have extremely low Nativity
is in this paper the woman that they
were pulling in this paper you know
we’re living over 100 year old so again
you know maybe during pregnancy you
suffer but you’re getting a lot of
payback from the Vettes so I just would
like to say that you know even if we do
you know even if I discover a pills for
anti-aging or Bank your stem cells there
is a lot of thing is that only one shot
and we’re going to cure everything so we
believe that down the road we can become
your personal trainer for aging so we
can stem
Bank your stem cells we can also Bank
your blood we can give you on teaching
drugs we can exercise it’s very
important but too much is not good so
you have to exercise the right way
nutrition is very important folks but
also you know like I said to people you
have to work with us if I give you the
best drug to delay aging but you’re
dressing like you know 20 year older and
you are then you’re gonna look older so
I think you know all those thing
mediation yoga you know all player all
here too so I just would like to say
that maybe down the road we’re going to
become your personal trainer for LT
aging and I just would like to finish by
saying that science and heart can come
together at one point
so we know the word that down the road
maybe when you Bank your stem cells we
can make a very nice frame with your
home stem cells on it that you can
display in your house and when you’re
going to show this to your friend you
can say this is my stem cells here so
again you know I just would like to
finish by saying that you know you’re
probably noticed you know I’m Canadian
and everything that we do in Canada
relate to our tea so here is it good
occupy a place where the park is a great
occupier play where the park is
going to be so as scientists I can tell
you five five years from now seven year
from now you are going to have your stem
cells bank because that’s the right
thing to do so thank you very much for
your attention
[Applause]
[Music]
you
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