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Imparting Joy of Parenthood | Saarthak Bakshi | TEDxIIMKashipur


good evening everyone thank you for the
lovely introduction that will give him I
so wish I see would have been
International Finance Corporation
instead of international port city
center and I would have been on a hiring
spree or they’re looking at all the
young graduates that are there but since
that’s far away let me start it so most
commonly when you meet someone the basic
question that is asked is what do you do
and whenever someone meets me and my
simple answer is what do I do
any climis I am a patriotic person when
we started meeting in the campaign I
said why not
I’ll make babies in India campaign
started a baby though a scandalous as it
sounds it’s the most noble and Noble
thing that one Hindu I can tell you to
my personal experience thousands of
couples that I’ve seen who suffer from
infertility conundrum to the fact that
we are a population of 1.3 billion
people and there is no stopping us but
let me do you create I am helping to
those people who don’t even have a
single side it’s not the ones which are
having the fifth of the six that are
coming to us for the seventh try but
those people would be trying for five
six seven years and don’t have a single
child so what is it that we are going to
talk about in shaping the future as the
theme says IVF isn’t a jewel technique
it’s been there for decades this is
there’s nothing new and assisted B
product techniques as they say man has
to me needs they need to survive and the
need to procreate
I look after the second need the legacy
should move on as the dough goes we are
not producing a once you have a
undergoes more a and hangar neither the
way we produce politicians but I want to
give that joy of parenthood
to those parents that have been
suffering from infertility for a very
very long time we have already done like
for millions Norman
for thousands of people all across the
world not only in India and Southeast
Asia
Israel us we’re at a pinnacle of medical
technology in the ourselves our health
care needs are nowhere 9/2 less to any
other country but saying that it’s easy
now our UI idea suddenly see all these
forms of assistive adaptive techniques
it’s been there for a very long time I
wanna talk about something further
moving beyond what is it that we can go
for your horn than giving a baby and
live my term for that is a genetically
modified human being or a designer baby
I wanna now we have given countless
babies but Tandy now give you gently
engineer baby tell me enhance the human
race and I as a doctor or you as the
future parents can rejoin her together
and go on this road where we produce
designer babies also called genetically
humans engineered babies we already need
them in test tubes burst now let’s take
it forward so but before moving forward
let’s take a let’s take a step backwards
in 90s before most of you were born I
went to the belief seventy will compute
about it
were the next added efficiency when
people would tell you then that that
point of time right
good fundings all transactions what we
turn to computers all banking deep in
matrimony
come to think of it if everything we
done by computers I would have costed
them if someone returning that in the
palm of your hand
supercomputer one day my would laugh at
all if in order in Toulouse we would
have spider red in the corner but if
someone would tell me that very soon you
would also have a bed in the center of
the room and by then I came to work
right then I will connect anyone and
everyone everything I would have just
being potassium but we have achieved
everything of that so moving from do is
leave 70s or the early eighties to this
we have achieved what we could not have
imagined or trade off
I signed a to date in terms of health
care shipping that future can we see the
baby simply design mankind can we
manufacture babies is the film that I’m
using sorry for my conditions but this
is where we are now looking forward to
so let’s move forward and discuss died
about so it’s nothing new
you have been engineering life for a
very long time
earlier selective breeding in plants and
animals has been long long ago it’s been
doing for hundreds of years it’s nothing
new by earlier engineering life we make
little breeding because at that point of
time we did not know those three
important words about my daily no not
the word that you using a quality moves
intently with your personal girlfriends
not those three words not that romantic
word I’m talking about DNA
deoxyribonucleic acid it is the essence
that important compresses me and
everybody
else these are essence of life wasn’t
figured out we were just engineering
life now we can modify it if I subtract
believe we can do everything with it so
give me something it is actually
scientific speaking it’s four pairs of
apgc molecules combined together to form
a chain a set of instructions with one
instruction and you change the beam
itself one tinkling here and there so
once that was figured out the next step
in human evolution as it is is
experimenting we started experimenting
with basic tinkering where I D suppress
radiation on two plants this was by
mutation II was just figuring out by
beating trial if something would have a
better hunting mode we had nothing to
lose by early seventies scientists have
figured out they had started putting DNA
step F snippets into plants and animals
and figuring out what modification of
what anything would be being and in 1974
the first genetically modified animal a
mice was born and I would like to say
that you should all thank that it was
Stewart Italy mice because to them we
have been able to produce countless
miracles and save billions of human
lives because of that anything
engineering we have been able to figure
out how to manufacture insulin we have
been able to manufacture growth hormones
life-saving protein factors and whatnot
moreover we have been able to
manufacture also produced 10s chickens
super muscle things
glow-in-the-dark fishes well the last
dozen tiny lose but it would put in your
aquarium or in your room and it’s very
cheap less than thousand rupees so you
can find your fluorescent zebra
easily around there having those kind of
users but that was this all has been
really remarkable but the only limiting
factor in all this is being there it’s
limited to the government gene editing
gene modification is very expensive I’m
consuming it’s a very long dick here to
understand the desire and desire to come
out it’s time very quickly hassles where
people will rule it when the government
allows image weather research lab will
dilute all of the funding would allow
there so what’s the use we do recover
the picture how can be as the youth
photo model do something about this so
now you guys have a chance as you I have
this time at the cusp of this technology
we are now I this juncture where three
to five years ago something very
revolutionary something very radical has
been discovered it’s called crystal
clustered regulated regularly
interspaced short palindromic reports
easy for us to understand isn’t that I
think you’ve enjoyed your ion drive so
if you don’t know Aaron let me explain
clusters is a revolutionary Gina
generating pool the table is the nuclear
age by sequentially targeting things
from these nucleuses by genomic level
we put it like the first question you
get in your iron that’s why you guys are
here I’m moving you should understand
that okay it’s Nora now let me actually
the human element down crisper or
Canadian whisper which helps you modify
geez
besides he quickly and easily in a way
discovered in fact ear it’s a protein
that was discovered in bacteria now to
make it understand it’s like I said that
poutine sciencism you can point if they
use it
scissor to cut the DNA and there will be
an RNA that will point to the location
where do you want to use that scissor
that’s all there to it in simple words
it’s a word processor for genes would
you identify the gene you I believe
subtract modified do the whole addition
dilution for the G and use that irony
why why would why the full word itself
or why the gene do thing he will do the
letter or as I said ATG see everything
is possible
and to the best of it it’s possible in
all species so CRISPR has not really
mealy easy quick and successful it has
brought down the force by pooping 99%
it’s accessible instead of it a few labs
at thousands of labs
it’s access to be able to you guys if
you want to do something crane with your
future generations but the next the
commercial application is not there
right now
so when Chris Paul has actually brought
the genetic gene modification or genetic
engineering in
how can that be used in to our normal or
everyday life really making a very
aesthetic about it
vanity about them that you know my
future the missions I want a blue-eyed
baby blonde hair you notice I have
healthy legs of the same poor or the
vocal cords of Beyonce you can’t control
that that is not possible what we want
to do today is be make some better human
weights what we really want is to
eradicate certain rare diseases for ever
we want to make chemically modified lima
beans what if I tell you that today if
you had a chance you can remove the
truth-finding the strands of DNA that
caused the sickle cell anemia chemo
failure thrombosis Down syndrome all
these genital diseases that are passed
on to one another what if we could cut
that out I our future generations can
you free of those diseases that is what
I mean by design a baby we have to
target that and not go for I know today
it isn’t
let’s go back to the example when I said
about mobile phones and computers and in
a sense a stage our technology isn’t
that nation C stage the experiments of
human-induced have not been allowed on
the government as of now so we are
active testing it on plants and animals
but in 2015 the first experiment was
done by the Chinese the Chinese
government of the Chinese scientists the
second will done in 2016 which was
successful so we already have human
embryos
genetically modified and we were
successful member
think of the implications that we can
add we’re tired and people broader their
vacations that you want to produce
arrays which food probably there is
Vince I mean that’s really far place
probably 500
the line but if you let your mind open
you can achieve anything with this power
of this technology deep it’s like a
pretty little box I want to say that I
want to have better human beings but I
really want that those skills should not
be used for aesthetic purposes as I said
but it’s you can’t overheat design human
beings as I say you want them to make
them better people but you can’t control
the technology so if someone who wants
that can I have the footballing skills
of Messi or can I have the Cricut
accessible arconi
those are things which are not embedded
in genes those are some things which you
can never control there are always
physical traits and the physical
characteristics that you will always be
able to control but not this aspect so
my point
over all this about shaping the future
is that you can shape healthcare when I
started in the business of making babies
as you say the first idea baby was born
in 1978 Louis brown in UK so it’s been
almost four decades and there has been
more than six million babies that have
been produced ydf imagine it took only
four decades and six million for this
technology to advance imagine how much
time will it take once we produced our
genetically modified human beings or
designer babies how much time would it
take for it to become a brilliant people
technology how many time we take where
we would all be six feet high
muscular brain has the stamina IP would
be the real hair fall will have great
digestion McCann
I mean this is limitless you you the
great Gordon goddesses would come back
down to earth as simply a like imported
so in the end I would like you to say
that we do we use this technology to
make people better or do we use this
technology to make better people thank
you [Applause]
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