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How has the DNA revolution impacted all of us? | Mechelle Wu | TEDxCanadianIntlSchool


dead dead dead

everyone and everything dies eventually

until they don’t

in the book of disquiet Fernando Pessoa

has said my soul is a hidden Orchestra I

know not what instruments what fill

strings and harps drums interval I sound

inside myself I here is a symphony what

if I told you someone out there

deciphered your symphony no not just

that they’ve mastered it it’s techniques

the beauty and flourish of the piece yet

to be perfected and still the making but

nonetheless existing this was in 1982

was it seemingly limitless possibilities

to even immortality the notion of

genetic manipulation artificial cell

replication the DNA revolution still

unknown and quite on from there to the

few whose curiosities were claimed

claimed by the study of just how much we

could push the boundaries of nature as

we know it well some still seek the

secrets this world so hold others others

fear for the unforeseen future if your

unknown but what is held in the power of

the words we speak and if the control of

life and death is too much for us to

handle according to the World Health

Organization 725 thousand individuals

are killed each year by the so-called

monster that is mosquito seven hundred

twenty five thousand that’s more than

the total population of Seattle

Washington that’s approximately two

hundred and forty-two times our school

population of 3,000 students and for

something that has been a problem for so

long and it’s pretty much a perennial

problem efforts have come a long way

since the first preventive and treatment

Aastha Tech is a biotechnology company

working with what they believe to be the

solution to this issue by inserting a

self-editing self-limiting gene that is

altered to work only in insect cells the

male Aedes aegypti mosquito now have the

ability to pass on this change was

offspring when releasing the wild so

their heritage of this strain would in

turn caused them to die before reaching

adulthood therefore limiting the local

mosquito population in the face of major

outbreaks like Zika which was estimated

to result in the financial burden of 3.5

billion in 2016 this method will be

brought to use and as according to

Oxitec the facility trials they have

performed have demonstrated the

reduction of the wild population to up

to 90% but some sympathy that that’s not

enough that’s when the method of CRISPR

cast nine comes in not only our

scientists testing the waters of this

new form technology our mosquitoes but

other experiments have also been

conducted to correct major genetic flaws

in animal models including mutations

responsible for muscular dystrophy and

cystic fibrosis CRISPR casts nine when

it comes to the ability to successfully

and efficiently remove replace rearrange

and ultra the DNA of as according to the

National Geographic any living organism

even us as can be interpreted by its

name this genome editing tool composes

of two main molecules the first caste 9

an enzyme acting as a cellular scalpel

or scissor and the other acting as a

navigation tool deriving from the unique

sequence found in bacteria and other

organisms that essentially target and

destroy the genome of invading viruses

this is a form of power we’ve only ever

dreamed of

and as it turns out the fountain of

eternal youth and immortality might not

she wants me or gifted he wants to be

and feel more beautiful they want to be

more intelligent we want to be more

athletic we don’t want to get sick we

don’t want to die young we don’t want to

go through the suffering as our bodies

tear it into nothingness until it can no

longer support itself until we have no

time left maybe we don’t want to die at

all as recent editing of human genome

has reached headlines so has the

controversy and troubling into

implications it brings with it what will

happen in a world where the wealthy get

their hands on the newest genetic

enhancements for their children from

designer bags to designer babies many

believe that this will be the source of

greater inequality to the point of

genetic discrimination as stated by the

fish incorporation eventually with the

rest of the world in tow the potentially

misuse of this technology for eugenics

the Han sment of certain human

characteristics as also herring thought

most how would our society function was

our perception of identity obscured how

would we compare instead of helping us

build a well-balanced and more open

minded society it might bring upon the

downfall of our economy and society as

we know it in the 10 years moving

forward regardless of objection and

disapproval or support and encouragement

the scientific world will keep on

changing and evolving as some things are

just inevitable but the ethical concerns

in mind is also important to note the

Starling and the saree innovations that

this technology has and will be

making that arguably outweigh the

potential risk of misuse that can be

avoided with adequate control and

regulation we like to say our heart

skips a beat at you when a pretty person

walks by or simply we were under a lot

of pressure for tests we didn’t

particularly sunny for but we don’t

truly understand how Sears who came

we’re making at that exact moment on

August 2nd

merely more than a month ago American

scientists successfully edited a human

embryo to remove to remove the Harriton

form of a heart disease HCM or a

hypertrophic cardiomyopathy affecting

one in 500 individuals this thickening

of your heart muscles makes it stiff and

unable to pump blood through your heart

and around your body which further

raises the question of whether

implementing this genetic tool is more

beneficial than not and what our future

will be like with it as this method is

used to eliminate sources of disease

will scientists continue until it

eliminates all causes of death this is

just the beginning living forever

something we dreamed of for since the

beginning of time eliminating genes that

contribute to higher risk of

cardiovascular diseases genetic

mutations hiv/aids enabling the transfer

of pig organs to humans suddenly all

this seems just within our fingertips

ready for us to grasp an Darkness the

power of DNA is like a computer program

but far far more advanced than any

software ever created Bill Gates said

this in his book the road ahead the

question is and forever will be

if we’re able to recreate something of

such proportion should we thank you for

listening [Applause]

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