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Cocaine in out | Luigi Gallimberti | TEDxPadova


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in the world there are 22 million
cocaine users
of these 9 are distributed in the
Americas and 5 million in Europe because the
cocaine that seems to continue to expand
non-stop to this great appeal in the
comparisons of the inhabitants of ours
planet answer is quite simple
because it produces a great pleasure a
pleasure that is tremendously similar to
that of the first love and therefore a
pleasure that we all remember is that everyone
we would like to try again when the
we tried the first time but if
perhaps for this reason cocaine
it would be both a problem but relatively
the problem as you see here is related to
fact that this substance besides
producing pleasure reduces functionally
that is, the efficiency of a part a lot
important in the brain that is the part
the prefrontal cortex is called
prefrontal the cortex because behind
at the front and is about a third
of the brain a third of the brain that
carry out the very important functions in
all mammals because it has a good one
operation of this part of the
the survival of the brain is linked
mammal man and woman included in the
time when cocaine
it does decrease this functionality
our consciousness our capacity
our ability to make decisions
to control the pulses is reduced
progressively and inexorably
and this is the reason why
rightly the addiction to cocaine
today
of the most advanced neuroscientists
It is considered a real one
toast there is a disease a disease
mental as we tried to
to curb cocaine in these decades
in the meantime, everything that has been done is not done
has passed the screening of effectiveness e
the things that have been done can be
grouped into three groups the drugs for
try to reduce desire
the intensity of pleasure , psychotherapy
who tried to face the
any conflicts problems that
they could be behind the insurgency
attraction for cocaine and facilities
rehab that they have tried to
re-educate the behaviors that were
went completely out of team for
cocaine fault but none of the three
systems neither separately nor together
they worked in the fourth canto
of the hell of the divine comedy a
certain democratic philosopher that the world
that the case in the world places that is
states that the world is the universe are
due nothing but the meeting of the
case and necessity was put by
giving in hell in an extraordinary
judicial error because it is not
he deserved it at all
since then and even before the world e
the whole universe is born develops itself
expands precisely because chance and necessity
they meet and also the story that I am
to tell you part of a case that is
content in this piece of newspaper is
a piece of the rest of the pug of 13
April of the
2013 when the father of a patient a
doctor thought up and 32 years dependent
from crack that had been entrusted by a
couple of years depending on the crack but that
he continued to be a doctor
imagine the problems that
we had to face arrived in this
piece of newspaper what contains the
ray that will defeat cocaine is the
title of the article that tells in a
experiment done in the United States by
a certain antonello bonci that does not
I knew an Italian who had been for 15 years
in the United States to manage the national
institute on drug abuse which was that it is the
the most important center in the world for it
addiction study what
he told this newspaper
in this article in the interview the
neuroscientist said that a group of
rats made addicted to cocaine
think that once dependent rats
from cocaine they come to press up to
2.000 times an hour the lever to get hold of
cocaine after having been
subjected thanks to a certain technique
newly invented invented call
the genetic facet had lost
the interest in his room as it was
could this happen you know that
the rat you know
and if you do not know, I’ll tell you in the
rat exists the system of pleasure that
hundreds of times smaller than the
man’s pleasure system more or less
done in the same way it is called
limbic system from this part of the
brain that is in the belly of the
all passions are born of the brain
love hate the desire for sex la
hunger thirst and so on
what did the pathogenetic it
all genetic is a science
revolutionary discovery stanford from the da
a psychiatrist gift named card slot the
which he has inserted in a certain way
ghana that of the small channels in the
rat brain cells and this
insertion has made these cells
sensitive to light was sufficient
insert an optical fiber into the brain
of the rat as big as a hair
turn on the light and the cells of the
limbic system because this system
genetically determined allowed to
sensitize with extreme precision
any part of the brain and it was
chosen limbic has entered once that
its that its sensitized part
been struck by the light has stopped
look for cocaine
evidently a ray of light ai
American laboratories must be must
have also hit my bark
prefrontal because from that moment on
then
I too have no longer known limits and
I ventured like everyone else
they asked how you got to do it
I do not know how to go from man to rat
to the man trying to get results
similar to those obtained on the ramps a
rat but can not use the car
Invasive technical genetics not
authorized and I thought about doing it
through stimulations and
magnetic impulses then you see that there is
a probe that a probe where one passes
electric current and puts stimulation
magnetic and these stimulation
Magnets end up on the system
limbic that of the rat where he went to
finish the light of the genetic opto system
and everything left to assume that we would have
obtained results similar to those
obtained from bonci with his
experiment and here is the tms room
in four and four completely
say a little out of the team I am
organized to get me this
system
and here it is made up of one
comfortable armchair that resembles that of a
dentist chair that serves for the
patient of 3 ass
the series a si with comfortably until
lying down is identified with great
precision thanks to the neuro navigator
a big part more or less like one
two euro coin on the left temple
part that is hit by 12 minutes of
electromagnetic waves of london in
magnets that gave the result
that we observed in mice the first
patient that we have treated in this
way
we called her a woman of Beatrice
38 years since the age of fourteen yes
He was continuously cocaine was
sitting on this armchair after 12 minutes
of treatment has opened up i
eyes and I made a big smile that
he told us something happened in
extraordinary I no longer want to
cocaine
I do not think about cocaine ball anymore if I think
I do not want to do anything with cocaine anymore
He had never successfully turns as
we may have stayed there
seeing something like this
we had exceeded all limits because
passing from the mouse directly to the human
as then there was also recognized a
international level
It was not so much for granted and
we immediately got busy
we have produced a first job
scientific made on a small sample
pilot 16 patients treated with tms e
compared to the treatment of 16
patients treated with drugs and also
here we have noticed that those treated
with what messengers they had
an extraordinarily superior figure
to others and from this moment on i
patients have as it was more or less a
react as beatrice had reacted
first became tens then hundreds
now we have almost exceeded 500
people but it would be a mistake to make you
believe that everything went smoothly like
someone said before
those who exceed the limits pay a pledge
and we too have paid the pledge
first we had to pay was
we have been charged by one
fifth of patients who did not want to
learn to stop using cocaine
and despite all ours
technical manipulations
technological we could not get them
resign
and so we turned to gods
psychoanalysts who have helped us
study the problem they took in
I load these patients and many of them
thanks to the joint intervention that ms
which it is made all the patients
plus this 20 percent helped in
specific way from an intervention
psychoanalytic psychotherapist have
finally surrendered and they stopped too
their
most of them use cocaine
obviously the news has done a bit
around the world
we have been contacted by the newspapers
very important type of science and type
national geographic wanted
knowing has worked well with them for
months has been a very nice experience
to make us interview to do
interview our patients in
September of last year the two
newspapers have come out national geographic
he gave us the cover and in 23 languages
has translated our experience around
for the whole world and from that moment on
then our fame with great
satisfaction but great fear aside
ours has suddenly increased
because fear alive
thank you because the fear
the fear is because we were
sure that things worked but
you know that in the choice you can not
work only on the observatory to have the
given the scientific data and we had
worked for years collecting data in
very precise way and delivering them
all to the United States of America where
independent experts have studied them
processed the works is a few
weeks have arrived and have
proved that on a sample of 200
patients that a great champion
observed for 24 months ie two years that
almost a whole period
of the patients had completely
stopped the use of cocaine
at this point we have the awareness
important that we have opened a fourth
away a fourth way that to all
guarantees to make you suspect that it could
be the right way to defeat
definitely a fourth cocaine
away you do not
not that it does not replace the
previous three but can be joined
further increasing effectiveness
of the tms from this moment on the
our team was then 3 4
people became tens of people
between doctors psychiatrists neurologists
psychoanalysts technical psychologists of
statistical laboratory to have you
administrative provisions, etc.
and all this divided team
predominantly between us and the states
united decided to put everyone together
their efforts to bring this
the technique to be diffused the most
possible in the whole world to be able to
replicate the results we have
got us but we explained the
we are explaining to all those who are there
they ask to be able to work like us
man is not just the brain that
man is made of brain and mind the
body and heart and we must take care of it
of the whole person if we want that
this person finds the strength of
completely abandon cocaine
but not only of the person also of the
family and also of the community
within which cocaine is
widespread
this will be destined to lead to that
cultural change that will allow
many people save you s from having it
life saves and to many other people
certainly have redeveloped it thanks
congratulations charming professor is
one of the beauties of ted can know
almost first that one was discovered
something as important as she used to say
individual well-being and health
collective I think you’ll understand why
I say that if this thing spreads it will have
you also need the guards of the
body
I already have already succeeded but already
there was my son I offer myself
continually less real guard door
thank you goodbye
however there are those who make people cry
who does enjoy I’m one of those
he did enjoy more than cry not
because she tells me so now hand
that I come away with her immediately find a
another presenter thanks professor
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