NIR Barzilai has been studying a group
of exceptionally healthy hundred year
olds or centenarians hi Milton so nice
meeting you or he believes they’re a
model for how we can all age come on in
fellas are you one of the interesting
thing with those centenarians is to see
how they interact with environment and
we thought hey maybe they do all the
right things
do you eat something special do you know
I try to keep a healthy diet what about
exercise exercise I walked about a
quarter of a mile but breakfast I swam
every day so my body has always been
activated and when you look at the
population you find almost the opposite
I go every I just about every year
afternoon the Dunkin donut and I have
coffee there and a Boston cream that
sort of thing your eating habits are not
necessarily healthy that’s true I smoked
for minus 40 so 50 is 50% of them or
beasts 50% of them do not exercise 60%
of the men and 30% of the women are
smoking so it’s in spite of all that
that they have some protection that
allows them easily to get to age 100
what we do find that they have is genes
that are protecting them against
anything that’s thrown their way those
are individual cells that have a
mutations we think are associated with
longevity and we follow what those
mutations are doing to the cell what
happens when you put the cells into a
hostile environment the reason we’re
looking for those mutations is that we
think that those mutation will slow the
rate of Aging Barzillai believes from a
biological perspective his centenarians
are aging slower than the rest of us
his plan is to prove that medications
can make us all age more like them when
you do genetic study the public things
that we need genetic treatment for those
diseases but not we cannot change your
genes so that you become 100 years old
but we can design medications based on
our knowledge that will interfere with
this pathway and interact intervene and
delay the effects of aging
of exceptionally healthy hundred year
olds or centenarians hi Milton so nice
meeting you or he believes they’re a
model for how we can all age come on in
fellas are you one of the interesting
thing with those centenarians is to see
how they interact with environment and
we thought hey maybe they do all the
right things
do you eat something special do you know
I try to keep a healthy diet what about
exercise exercise I walked about a
quarter of a mile but breakfast I swam
every day so my body has always been
activated and when you look at the
population you find almost the opposite
I go every I just about every year
afternoon the Dunkin donut and I have
coffee there and a Boston cream that
sort of thing your eating habits are not
necessarily healthy that’s true I smoked
for minus 40 so 50 is 50% of them or
beasts 50% of them do not exercise 60%
of the men and 30% of the women are
smoking so it’s in spite of all that
that they have some protection that
allows them easily to get to age 100
what we do find that they have is genes
that are protecting them against
anything that’s thrown their way those
are individual cells that have a
mutations we think are associated with
longevity and we follow what those
mutations are doing to the cell what
happens when you put the cells into a
hostile environment the reason we’re
looking for those mutations is that we
think that those mutation will slow the
rate of Aging Barzillai believes from a
biological perspective his centenarians
are aging slower than the rest of us
his plan is to prove that medications
can make us all age more like them when
you do genetic study the public things
that we need genetic treatment for those
diseases but not we cannot change your
genes so that you become 100 years old
but we can design medications based on
our knowledge that will interfere with
this pathway and interact intervene and
delay the effects of aging
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